Human seminal plasma hypersensitivity is also known as semen or sperm allergy. This refers to an untoward reaction to certain proteins in semen. It is a relatively rare yet a problematic disorder. And interestingly, semen allergy can occur in both the female and the male.
This happens when the body's immune system overreacts when it encounters semen. The white blood cells mistakenly identify proteins in the semen as harmful invaders like bacteria or some viruses. Thus, the white blood cells launch an attack with these.